TB-500 10 mg research peptide vial from SilverLeaf Bio
SilverLeaf Bio TB-500 10 mg research vial top view
SilverLeaf Bio TB-500 10 mg research vial on kitchen countertop
SilverLeaf Bio TB-500 10 mg research vial angled view

TB-500

Recovery / Healing
Actin-Regulating Repair Peptide
Actin • Cell Migration • Tissue Remodeling
  • Studied for actin and cell-migration pathways
  • Researched in tissue-repair and remodeling models
  • Associated with angiogenesis and wound-healing research
  • Used in recovery and connective-tissue research contexts
10mg

$74.99

Availability: In stock

For research purposes only.
Reconstitution Calculator
Emma Lindsay research guide in a white lab coat with a steel blue blouse

Emma Lindsay

RESEARCH GUIDE

I’ve pulled together the key product details, research context, and supporting information so you can quickly decide whether this item lines up with your research goals.

Overview

TB-500 is a research peptide studied mainly for tissue repair, recovery, cell migration, and wound-healing biology. In plain English, researchers are interested in TB-500 because it is associated with processes that help cells move into damaged areas, reorganize tissue, and support repair after injury. This makes TB-500 especially relevant to research involving soft tissue, muscle, tendons, wound healing, and broader recovery-related pathways.

Scientifically, TB-500 is a synthetic peptide associated with thymosin beta-4 research and is studied for its effects on actin regulation, cell migration, angiogenesis, inflammatory signaling, and extracellular matrix remodeling. Its research profile includes endothelial-cell movement, tissue regeneration, wound closure, and cytoskeletal organization. Because much of the evidence is based on thymosin beta-4 and preclinical models rather than large controlled human trials of TB-500 itself, it should be positioned as an investigational tissue-repair research peptide rather than a proven therapeutic agent.

The Science Behind TB-500
Explore how TB-500 is studied through actin regulation, cell migration, angiogenesis, and tissue-repair pathways.
TB-500 is studied as a synthetic fragment associated with thymosin beta-4 biology, a naturally occurring peptide involved in actin regulation, cell movement, angiogenesis, and tissue-repair signaling. In research models, thymosin beta-4 has been examined for its ability to influence cytoskeletal organization, support cell migration, and participate in the repair environment that develops after tissue injury. This makes TB-500 most relevant to studies focused on soft-tissue remodeling, wound-healing biology, tendon and ligament research, and recovery-related cellular movement.

The scientific interest around TB-500 comes from its relationship to actin dynamics. Actin is a major structural protein involved in cell shape, movement, and repair responses. Research involving thymosin beta-4 has shown activity in keratinocyte migration, endothelial cell behavior, collagen deposition, and angiogenesis in preclinical wound models.
Is TB-500 Right for Your Research Goals?
Discover how TB-500 fits into tissue-repair research and what considerations may be important before selection.
TB-500 may be relevant for research goals focused on actin regulation, cell migration, connective-tissue remodeling, wound-healing pathways, angiogenesis, and recovery-related tissue biology. It is commonly discussed alongside BPC-157 because both peptides are studied in repair-focused models, but they are associated with different biological themes. TB-500 is more closely tied to actin dynamics and cell movement, while BPC-157 is often discussed in relation to cytoprotection, angiogenesis, and gastrointestinal or tendon-related repair models.

TB-500 also requires careful research-context consideration because it is not an approved therapeutic product and human safety data remain limited. Research contexts involving active or suspected malignancy, abnormal blood-vessel growth, uncontrolled inflammatory disease, pregnancy or breastfeeding, significant immune reactivity, cardiovascular instability, or sensitivity to injectable research materials deserve additional caution and professional review.
Dosage, Reconstitution & Storage
General researcher-reported dosing ranges, reconstitution, handling, and storage information to help maintain peptide integrity.
TB-500 does not have an approved clinical dosing label. Published thymosin beta-4 research includes topical and experimental study designs, but those clinical-study formats should not be treated as direct dosing instructions for TB-500. In researcher-reported exploratory settings, TB-500 is commonly discussed in the range of approximately 2-5 mg per week, sometimes divided into one or two weekly research exposures over a 4-6 week loading-style window. Some longer exploratory protocols describe lower maintenance-style exposures, such as approximately 2 mg weekly, after an initial study period. These ranges should be understood as research-context references only, not as recommended use. Protocol design depends on the study model, application, concentration, target tissue, observation window, and safety controls.

For storage and handling, TB-500 should follow standard peptide-integrity practices. Store unopened lyophilized vials refrigerated when possible and protected from direct light, heat, and repeated temperature changes. Once reconstituted, keep refrigerated and avoid unnecessary warming, freezing, or repeated agitation. If mixing is needed after adding diluent, gently swirl the vial rather than shaking it. Aggressive shaking can create foaming and may reduce peptide integrity over time.
-SILVERLEAF MULTI-BUY OFFER-

BUY 4.
GET 1 FREE.

Add any 5 eligible peptides to your cart. The lowest-priced item is automatically free.

No coupon code required.

Researched in Combination With TB-500

Product image for the SilverLeaf Bio V2 Peptide Pen Starter Kit, showing the research support pen, cartridge, and needle components in a clean product presentation.
BPC-157
10mg
$69.99
SilverLeaf Bio GHK-Cu 50 mg research vial front view
GHK-Cu
50mg
$59.99
KPV 10 mg research peptide vial from SilverLeaf Bio
KPV
10mg
$69.99
V2 peptide pen starter kit with white travel case, glass cartridges and pen needles
V2 Peptide Pen Starter Kit
$49.99

Research Guides & Resources

Canadian couple using Shakepay to make a Bitcoin payment

How to Pay With Bitcoin in Canada

Follow a simple step-by-step guide to buying Bitcoin in Canada and completing your SilverLeaf Bio order securely.

READ article
Laboratory bench with pipettes, sample tubes, assay plate, and research equipment for peptide research methods

Peptide Research Beginner’s Guide

Learn the basics of peptide research, including reconstitution, measurement, handling, record-keeping, and good research practices.

READ article

Questions About This Peptide?

Meet NOVA — Your AI Research Assistant

Get instant answers about peptide biology, research applications, storage requirements, research pairings, shipping details, and more.

  • What does this peptide do?
  • Is it right for my needs?
  • What can it be stacked with?
  • How do I store it/ reconstitute it?
  • How long does shipping take?
ASK NOVA

Trained on SilverLeaf Bio product information, educational resources, and research content.

Third-Party Tested

Quality you can trust.

FREE Shipping

On all Orders over $300

Earn Rewards

Collect points on every purchase

Canadian Focused

Family Owned & Operated

Shopping Cart
Ask Nova Ask Nova